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Tracking Polymorph & Crystal Morphology

Crystallization is a commonly used process for solid-dose manufacturing. To improve the biological performance and economic benefits of a crystallization process, proper process control is necessary. However, crystallization can be difficult to control due to the complex relationship between thermodynamic and kinetic factors and processes such as nucleation, growth, and agglomeration. A thorough understanding of the process is required, which can be done through modeling, design of experiment stress testing and the use of process analytical technologies (PAT).

We invite you to read more about the Tracking Polymorph & Crystal Morphology with High Throughput Raman for Process Understanding & Control application note, featuring a collaboration with Technobis.

If you would like to discuss your application and are considering adopting Raman spectroscopy as a process analytic technology, please contact us at [email protected]