Faster, High-Precision Measurement

Raman spectroscopy has proven to be a technological innovation in the pharmaceutical industry by becoming one of the most popular analytical measurement tools. Coupled with chemometrics methods, it has significant advantages of high sensitivity and resolution in pharmaceutical quantitative analysis. It can be used in the characterization of drug molecules to revealing solid, liquid and solution phase samples arising from polymorphism and quantitative applications in formulations.

Lab worker inspecting gauge on equipment

Real-time process analysis for your pharmaceutical manufacturing needs

Tornado’s HyperFlux™ PRO Plus is currently in use across the globe in both batch and continuous pharmaceutical manufacturing. What’s unique about our technology is that the HyperFlux™ PRO Plus uses a proprietary HTVS™ enabled spectrometer to deliver better Raman sensitivity than ever before possible, designed to provide users with faster measurements (10x to 30x) for better process responsivity, better sensitivity for lower detection limits, and permitting reduction of the laser power without sacrificing performance.


  • API analysis & formulations
  • Crystallization
  • Blending
  • Amorphous Solid Dispersion (ASD)
  • Kinetics

Contact a Tornado expert to discuss your application:


Improving quality, efficiency, and chemical process economics using HyperFlux™ PRO Plus real-time reaction monitoring

In this application note, a major pharmaceutical company needed to monitor the conversion of benzoic anhydride to the corresponding ester. We present how Tornado’s HyperFlux™ PRO Plus provided a fast and accurate monitoring tool to confirm reaction quality and optimize reaction timing.